Xenosaga: The Animation

The year is T.C. 4767. Four thousand years after humanity left its homeworld, Earth, people now face annihilation from a hostile alien force called the Gnosis. In a desperate attempt to survive, Vector engineer Shion Uzuki creates KOS-MOS, a highly advanced android designed to fight this threat. But when the Gnosis destroy their ship, Shion and her allies are caught in a conflict where friend and foe are no longer easily distinguished.